A team of kayakers sets out to explore South America's major waterways. On Lake Titicaca the group visits two ancient Indian tribes. On the Urubamba River the team visits Inca ruins on its way to the famous Lost City, Machu Picchu. At Lago Argentina the team is granted permission to paddle out and film the massive Moreno Glacier, which collapses in a breathtaking spectacle once every four years. The film also includes a journey to the vast Iguazu Falls as featured in the film THE MISSION. The final part of the journey takes the group to Tierra del Fuego to trace the path of Charles Darwin's famous voyage of discovery to reach Ushuaia, the world's most southerly town.